1. Catecholamines and Hemodynamic Changes in Hypertension
نویسندگان
چکیده
منابع مشابه
Hemodynamic changes in hypertension.
DESPITE a vast amount of work devoted to the subject the nature of the fundamental hemodynamic changes in chronic, human hypertension is poorly understood. In this necessarily brief discussion the main outlines of the problem will be sketched in emphasizing the respective roles of the heart, large arteries and resistance vessels. Other factors such as the sympathetic nervous system, the barorec...
متن کاملCatecholamines and hypertension.
Ever since the demonstration that the active principle in the adrenal medulla can raise blood pressure (Oliver & Schafer, 1895), catecholamines have been implicated in the hypertensive diseases. The identity of noradrenaline as the neurotransmitter of sympathetic nerves (von Euler, 1946) and the demonstration that an injection of this catecholamine can produce cardiovascular changes similar to ...
متن کاملPlasma Catecholamines and Essential Hypertension
Of 78 comparative studies of plasma catecholamines in patients with essential hypertension and in normotensive controls, most reported higher catecholamine levels in the hypertensives, although only about 40% of the studies were positive (reporting statistically significant hypertensivenormotensive differences). Although there was dramatic variability in catecholamine values within and across s...
متن کاملFree and conjugated catecholamines in human hypertension.
1. Noradrenaline and adrenaline in the adrenal vein of essential hypertensive patients are almost exclusively (99%) unconjugated or free. However only 17% of dopamine is free, the rest is conjugated. The further the site of sampling from the adrenal vein the closer come the free catecholamines to their normal peripheral venous proportion (noradrenaline + adrenaline 20%, dopamine less than 1% of...
متن کاملSulfoconjugation of catecholamines, nutrition, and hypertension.
Sulfoconjugation is an important metabolic pathway determining the fate and potential cardiovascular action of ingested phenolic substances. Among the three catecholamines, dopamine (DA) is to the highest degree sulfoconjugated and has the highest affinity toward the phenolsulfotransferase (PST). The concentration of some sulfated catecholamines, particularly of DA sulfate, increases following ...
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ژورنال
عنوان ژورنال: Japanese Circulation Journal
سال: 1966
ISSN: 0047-1828,1347-4839
DOI: 10.1253/jcj.30.157